研究

研究室

講師:進藤 佐和子(シンドウ サワコ)

役職名

講師

研究室

環境衛生学

最終学歴

昭和大学大学院薬学研究科 博士課程修了

学位

博士(薬学)

専門分野

衛生薬学

所属学会

日本薬学会、日本毒性学会

研究業績1

Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia.
Sawako Shindo, Shih-Heng Chen, Saki Gotoh, Kosuke Yokobori, Hao Hu, Manas Ray, Rick Moore, Kiyoshi Nagata, Jennifer Martinez, Jau-Shyong Hong, Masahiko Negishi
Cell communication and signaling : CCS 18(1) 117-117 2020年7月29日

研究業績2

A phosphorylation-deficient mutant of retinoid X receptor α at Thr 167 alters fasting response and energy metabolism in mice.
Tatsuya Sueyoshi, Tsutomu Sakuma, Sawako Shindo, Muluneh Fashe, Tomohiko Kanayama, Manas Ray, Rick Moore, Masahiko Negishi
Laboratory investigation; a journal of technical methods and pathology 99(10) 1470-1483 2019年10月

研究業績3

Sulfotransferase 4A1 Increases Its Expression in Mouse Neurons as They Mature.
Takuyu Hashiguchi, Sawako Shindo, Shih-Heng Chen, Jau-Shyong Hong, Masahiko Negishi
Drug metabolism and disposition: the biological fate of chemicals 46(6) 860-864 2018年6月

研究業績4

Detection and Functional Analysis of Estrogen Receptor α Phosphorylated at Serine 216 in Mouse Neutrophils.
Sawako Shindo, Rick Moore, Masahiko Negishi
Methods in molecular biology (Clifton, N.J.) 1366 413-424 2016年

研究業績5

Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression.
Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa
Toxicology letters 219(2) 143-50 2013年5月23日

研究業績6

Serine 216 phosphorylation of estrogen receptor α in neutrophils: migration and infiltration into the mouse uterus.
Sawako Shindo, Rick Moore, Gordon Flake, Masahiko Negishi
PloS one 8(12) e84462 2013年

研究業績7

Phosphorylation of serine 212 confers novel activity to human estrogen receptor α.
Sawako Shindo, Tsutomu Sakuma, Masahiko Negishi, James Squires
Steroids 77(5) 448-53 2012年4月

研究業績8

MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor.
Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa
PloS one 7(7) e41291 2012年

研究業績9

Phosphorylation of estrogen receptor in reproductive organs of female mice
Sawako Shindo, James Squires, Tsutomu Sakuma, Tomohiko Kanayama, Rick Moore, Masahiko Negishi
DRUG METABOLISM REVIEWS 43 186-186 2011年11月

研究業績10

A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction.
Sawako Shindo, Satoshi Numazawa, Takemi Yoshida
The Biochemical journal 401(3) 735-41 2007年2月1日

研究業績11

Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital.
Satoshi Numazawa, Sawako Shindo, Keiji Maruyama, Fumika Chibana, Yosuke Kawahara, Takashi Ashino, Sachiko Tanaka, Takemi Yoshida
FEBS letters 579(17) 3560-4 2005年7月4日