研究

小田　絢子
(オダ　アヤコ)

所属
薬剤情報解析学
職位
助教
学位
博士（薬学）（明治薬科大学：2024年）

研究キーワード

  • バイオマーカー、薬物代謝酵素、質量分析

研究分野

  • 医療薬学

主な研究業績

  • Search for novel biomarkers to predict cytochrome P450 2C19 activity using untargeted metabolomics of human plasma. Metabolites, 16, 670 (2026)

    Oda A, Suzuki Y, Koyama T, Negami J, Suzuki S, Iino K, Yamagishi N, Kamio N, Ozaki E, Yamamoto Y, Nakatochi M, Momozawa Y, Tanaka R, Ono H, Sumimoto T, Tatsuta R, Itoh H, Takashima N, Matsuo K, Ohno K.

  • Discovery of novel plasma biomarkers for OATP1B1 activity using nontargeted metabolomics. Drug Metabolism and Disposition, 54, 100366 (2026)

    Negami J, Suzuki Y, Koyama T, Oda A, Iino K, Suzuki S, Yamagishi N, Kamio N, Ozaki E, Yamamoto Y, Nakatochi M, Momozawa Y, Tanaka R, Ono H, Sumimoto T, Tatsuta R, Itoh H, Takashima N, Matsuo K, Ohno K.

  • Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort. European Journal of Clinical Pharmacology, 82, 180 (2026)

    Tanaka R, Suzuki Y, Koyama T, Sumimoto T, Oda A, Sato H, Ozaki E, Tatsuta R, Yamamoto Y, Nakatochi M, Momozawa Y, Ohno K, Takashima N, Matsuo K, Itoh H.

  • Plasma coproporphyrins for evaluating OATP1B and OATP2B1 activities: Coproporphyrin-III unsuitable as an OATP2B1 biomarker in Japanese general population. Drug Metabolism and Disposition, 54, 100276 (2026)

    Negami J, Suzuki Y, Koyama T, Yamazaki M, Oda A,Ozaki E, Yamamoto Y, Nakatochi M, Momozawa Y, Takashima N, Matsuo K, Ohno K.

  • Post‑transplant trajectories and renal function associations of mid‑regional pro‑adrenomedullin, mid‑regional pro‑atrial natriuretic peptide, and copeptin in kidney transplant recipients. Peptides, 197, 171484 (2026)

    Iwao M, Tanaka R, Suzuki Y, Oda A, Ono H, Tatsuta R, Ando T, Shin T, Ohno K, Itoh H.

  • Ultra-sensitive quantification of indoxyl sulfate and 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in plasma using ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Journal of Clinical Laboratory Analysis, 39, e70077 (2025)

    Negami J, Suzuki Y, Sato H, Toyama D, Oda A, Tanaka R, Ono H, Ando T, Shin T, Itoh H, Ohno K.

  • Ultra-sensitive quantification of mid-regional proadrenomedullin in human plasma using micro-liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. ACS Omega, 10, 24214-24223 (2025)

    Suzuki Y, Koyama T, Negami J, Toyama D, Oda A, Tanaka R, Iwao M, Tatsuta R, Ando T, Shin T, Itoh H, Ohno K.

  • Evaluation of the usefulness of plasma 4β‐hydroxycholesterol concentration normalized by 4α‐hydroxycholesterol for accurate CYP3A phenotyping. Clinical and Translational Science, 17, e13768 (2024)

    Oda A, Suzuki Y, Sato H, Koyama T, Nakatochi M, Momozawa Y, Tanaka R, Ono H, Tatsuta R, Ando T, Shin T, Wakai K, Matsuo K, h, Itoh H, Ohno K.

  • Evaluation of effects of indoxyl sulfate and parathyroid hormone on CYP3A activity considering the influence of CYP3A5 gene polymorphisms. British Journal of Clinical Pharmacology, 89, 3648-3658 (2023)

    Oda A, Suzuki Y, Yoshijima C, Sato H, Tanaka R, Ono H, Tatsuta R, Ando T, Shin T, Itoh H, Ohno K.

  • Highly sensitive simultaneous quantification of indoxyl sulfate and 3‐carboxy‐4‐methyl‐5‐propyl‐2‐furanpropanoic acid in human plasma using ultra‐high performance liquid chromatography coupled with tandem mass spectrometry. Journal of Separation Science, 45, 1672-1682 (2022)

    Oda A, Suzuki Y, Sato B, Sato H, Tanaka R, Ono H, Ando T, Shin T, Mimata H, Itoh H, Ohno K.

所属学協会

  • 日本薬学会、日本医療薬学会、日本TDM学会、日本臨床薬理学会、日本医薬品情報学会

受賞

2024年9月 22th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, Best Clinical Toxicology Poster Presentation
2022年5月 第38回日本TDM学会・学術大会優秀演題賞

社会・学術貢献活動

  • 第34回⽇本医療薬学会年会 実⾏委員


研究者情報の詳細は
researchmap をご覧ください。

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