小池 伸
(コイケ シン)
研究キーワード
- 酸化ストレス
- カルボニルストレス
- 神経変性疾患・精神疾患
- 生体内硫黄種
- Sestrin2
- オートファジー
- LC-MS/MS
研究分野
- 分析化学
- 生化学
主な研究業績
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Capsaicin attenuates methylglyoxal-induced neurotoxicity via the ATF4–Sestrin2 signaling and direct scavenging of methylglyoxal
NeuroToxicology 114, 103444 (2026)
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Polysulfide and persulfide-mediated activation of the PERK-eIF2α-ATF4 pathway increases sestrin2 expression and reduces methylglyoxal toxicity
Redox Biology 79, 103450 (2025)
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Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex
Redox Biology 45, 102057 (2021)
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Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain
Brain research bulletin 144 164-170 (2019)
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Analysis of endogenous H2S and H2Sn in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection
Free Radical Biology and Medicine 113 355-362 (2017)
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Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation
Redox Biology 12, 530-539 (2017)
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Polysulfide exerts a protective effect against cytotoxicity caused by t-buthylhydroperoxide through Nrf2 signaling in neuroblastoma cells
FEBS letters 587 (21), 3548-3555 (2013)
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A novel pathway for the production of hydrogen sulfide from D-cysteine in mammalian cells
Nature communications 4 1366 (2013)
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【Review article】Analysis and characterization of sulfane sulfur
Analytical Biochemistry 687 115458 (2024)
所属学協会
- 日本薬学会
- 日本生化学会
- 日本神経精神薬理学会
