研究

山口　憲孝
(ヤマグチ　ノリタカ)

所属
細胞分子薬理学
職位
教授
学位
博士（薬学）

研究キーワード

  • がん
  • 炎症
  • 肥満
  • 骨格筋
  • 老化

研究分野

  • 分子薬理学
  • 細胞生物学
  • 生化学

主な研究業績

  • Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

    Yuki Takakura, Moeka Machida, Natsumi Terada, Yuka Katsumi, Seika Kawamura, Kenta Horie, Maki Miyauchi, Tatsuya Ishikawa, Nobuko Akiyama, Takao Seki, Takahisa Miyao, Mio Hayama, Rin Endo, Hiroto Ishii, Yuya Maruyama, Naho Hagiwara, Tetsuya J Kobayashi, Naoto Yamaguchi, Hiroyuki Takano, Taishin Akiyama, Noritaka Yamaguchi

    Nature Communications 15: 953 (2024)

  • Autophagy and proteasomes in thymic epithelial cells: essential bulk protein degradation systems for immune homeostasis maintenance

    Noritaka Yamaguchi, Yuki Takakura, Taishin Akiyama

    Frontiers in Immunology 15: 1488020 (2024)

  • VGLL3 activates inflammatory responses by inducing interleukin-1α secretion

    Yuki Takakura, Naoto Hori, Natsumi Terada, Moeka Machida, Naoto Yamaguchi, Hiroyuki Takano, Noritaka Yamaguchi

    FASEB Journal 35: e21996 (2021)

  • Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway

    Naoto Hori, Kazuyuki Okada, Yuki Takakura, Naoto Yamaguchi, Noritaka Yamaguchi

    Journal of Biological Chemistry: 295: 8798-8807 (2020)

  • Multiple roles of vestigial-like family members in tumor development

    Noritaka Yamaguchi

    Frontiers in Oncology 10: 1266 (2020)

  • Down-regulation of forkhead box protein A1 (FOXA1) leads to cancer stem cell-like properties in tamoxifen-resistant breast cancer cells through induction of interleukin-6

    Noritaka Yamaguchi, Yuji Nakayama, Naoto Yamaguchi

    Journal of Biological Chemistry 292: 8136-8148 (2017)

所属学協会

  • 日本薬学会
  • 日本薬理学会
  • 日本分子生物学会
  • 日本生化学会
  • 日本癌学会

受賞

2017年11月 Featured article in Biological and Pharmaceutical Bulletin
2017年5月 Journal of Biological Chemistry selected in Editors' Picks

社会・学術貢献活動

  • Frontiers in Oncology Associate Editor


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