研究

研究室

助教:大山 悦子(オオヤマ エツコ)

研究室 衛生化学
最終学歴 明治薬科大学薬学部衛生薬学科(1988年3月)
学位 博士(薬学) (明治薬科大学:2003年)
講義科目 衛生化学
専門分野 衛生化学、生物化学
研究課題 ヘビ毒中の血小板凝集抑制物質の研究 ヘビ毒中のプロテアーゼに関する研究 ヘビ毒中のセリン酵素に関する研究
所属学会 日本薬学会、日本生化学会、 International Society on Toxinology (IST)
学会活動 日本薬学会第128年会組織委員会委員(2007-2008)
研究業績1 Amino acid sequence of a thrombin like enzyme, elegaxobin, from the venom of Trimeresurus elegans (Sakishima-habu). Toxicon 40, 959-970 (2002)
研究業績2 Purification and characterization of a thrombin like enzyme, elegaxobin II, with Lys-bradykinin releasing activity from the venom of Trimeresurus elegans (Sakishima-habu). Toxicon 41, 559-568 (2003)
研究業績3 Amino acid sequence of a thrombin like enzyme, elegaxobin II, from the venom of Trimeresurus elegans (Sakishima-habu). Toxicon 44, 711-721 (2004)
研究業績4 Substrate specificity of two thrombin like enzymes (elegaxobin, elegaxobin II) from the venom of Trimeresurus elegans (Sakishima-habu). Toxicon 48, 601-610 (2006)
研究業績5 Distribution of low molecular weight platelet aggregation inhibitors from snake venoms. Toxicon 49, 293-298 (2007)
研究業績6 Amino acid sequence of a kinin-releasing enzyme, KR-E-1, from the venom of Agkistrodon caliginosus (Kankoku-mamushi).Toxicon 52, 651-654 (2008)
研究業績7 Purification and characterization of a new platelet aggregation inhibitor with dissociative effect on ADP-induced platelet aggregation, from the venom of Protobothrops elegans (Sakishima-habu). Toxicon 53, 706-712 (2009)
研究業績8 Primary structure and characterization of a non hemorrhagic metalloproteinase with fibrinolytic activity, from the venom of Protobothrops tokarensis (Tokara-habu). Toxicon 70, 153-161 (2013)
研究業績9 Purification and characterization of two platelet-aggregation inhibitors, named angustatin and H-toxin TA2, from the venom of Dendroaspis angusticeps. Toxicon 93, 61-67 (2015)
研究業績10 Purification and characterization of two high molecular mass snake venom metallotroteinases (P-III SVMPs), named SV-PAD-2 and HR-Ele-1, from the venom of Protobothrops elegans (Sakishima-habu. Toxicon 103, 30-38 (2015)