泉川　桂一（イズミカワケイイチ）

研究キーワード

SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis.

Ogawa A, Izumikawa K, Tate S, Isoyama S, Mori M, Fujiwara K, Watanabe S, Ohga T, Jo U, Taniyama D, Kitajima S, Tanaka S, Onji H, Kageyama SI, Yamamoto G, Saito H, Morita TY, Okada M, Natsumeda M, Nagahama M, Kobayashi J, Ohashi A, Sasanuma H, Higashiyama S, Dan S, Pommier Y, Murai J.

Mol Cell. 2025. 85(5):894-912.e10. doi: 10.1016/j.molcel.2025.01.008. Epub 2025 Feb 4.
LYAR potentiates rRNA synthesis by recruiting BRD2/4 and the MYST-type acetyltransferase KAT7 to rDNA.

Izumikawa K, Ishikawa H, Yoshikawa H, Fujiyama S, Watanabe A, Aburatani H, Tachikawa H, Hayano T, Miura Y, Isobe T, Simpson RJ, Li L, Min J, Takahashi N.

Nucleic Acids Res. 2019. 47(19):10357-10372. doi: 10.1093/nar/gkz747.
TDP-43 regulates site-specific 2'-O-methylation of U1 and U2 snRNAs via controlling the Cajal body localization of a subset of C/D scaRNAs

Izumikawa K, Nobe Y, Ishikawa H, Yamauchi Y, Taoka M, Sato K, Nakayama H, Simpson RJ, Isobe T, Takahashi N.

Nucleic Acids Res. 2019. 47(5):2487-2505. doi: 10.1093/nar/gkz086.