研究

月村　考宏
(ツキムラタカヒロ)

所属
機能形態学
職位
講師
学位
博士（薬学）

研究キーワード

  • 遺伝病、先天代謝異常症、リソソーム病、遺伝学、生化学

主な研究業績

  • Use of a mouse–human chimeric anti-α-galactosidase A monoclonal antibody as a reference for measuring serum antidrug antibody titers in patients with Fabry disease.

    Tsukimura T, Kami D, Shiga T, Togawa T, Gojo S, Sakuraba H.

    Mol. Genet. Metab., 144, 109000, 2025.

  • Comparative study on incorporation of three recombinant human α-galactosidase A drugs (agalsidases) into cultured fibroblasts and organs/tissues of Fabry mice.

    Tsukimura T, Shiga T, Togawa T, Sakuraba H.

    Mol. Genet. Metab. Rep., 40, 101118, 2024

  • Does administration of hydroxychloroquine/amiodarone affect the efficacy of enzyme replacement therapy for Fabry mice?

    Tsukimura T, Saito K, Shiga T, Ogawa Y, Sakuraba H, Togawa T.

    Mol. Genet. Metab. Rep., 39, 101079, 2024.

  • Profiles of Globotriaosylsphingosine Analogs and Globotriaosylceramide Isoforms Accumulated in Body Fluids from Various Phenotypic Fabry Patients.

    Shiga T*, Tsukimura T*, Kubota T, Togawa T, Sakuraba H. (*Equally contributed )

    Intern. Med., 63, 1531-1537, 2024.

  • Comparative urinary globotriaosylceramide analysis by thin-layer chromatography-immunostaining and liquid chromatography-tandem mass spectrometry in patients with Fabry disease.

    Shiga T*, Tsukimura T*, Namai Y, Togawa T, Sakuraba H. (*Equally contributed )

    Mol. Genet. Metab. Rep., 29, 100804, 2021.

  • Does administration of hydroxychloroquine/amiodarone accelerate accumulation of globotriaosylceramide and globotriaosylsphingosine in Fabry mice?

    Tsukimura T, Shiga T, Saito K, Ogawa Y, Sakuraba H, Togawa T.

    Mol. Genet. Metab. Rep., 28, 100773, 2021.

  • Anti-drug antibody formation in Japanese Fabry patients following enzyme replacement therapy.

    Tsukimura T, Tayama Y, Shiga T, Hirai K, Togawa T, Sakuraba H.

    Mol. Genet. Metab. Rep., 25, 100650, 2020.

  • Plasma mutant α-galactosidase A protein and globotriaosylsphingosine level in Fabry disease.

    Tsukimura T, Nakano S, Togawa T, Tanaka T, Saito S, Ohno K, Shibasaki F, Sakuraba H.

    Mol. Genet. Metab. Rep., 1, 288-298, 2014.

  • Efficient uptake of recombinant α-galactosidase A produced with a gene-manipulated yeast by Fabry mice kidneys.

    Tsukimura T, Kawashima I, Togawa T, Kodama T, Suzuki T, Watanabe T, Chiba Y, Jigami Y, Fukushige T, Kanekura T, Sakuraba H.

    Mol. Med., 18, 76-82, 2012.

  • Uptake of a recombinant human alpha-L-iduronidase (laronidase) by cultured fibroblasts and osteoblasts.

    Tsukimura T, Tajima Y, Kawashima I, Fukushige T, Kanzaki T, Kanekura T, Ikekita M, Sugawara K, Suzuki T, Togawa T, Sakuraba H.

    Biol. Pharm. Bull., 31, 1691-1695, 2008.

所属学協会

  • 日本薬学会
  • 日本先天代謝異常学会
  • 日本生化学会

研究者情報の詳細は
researchmap をご覧ください。

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