小川　泰弘（オガワヤスヒロ）

所属: 薬効学

職位: 准教授

学位: 理学博士(総合研究大学院大学)

研究キーワード

神経障害アストロサイト

研究分野

ライフサイエンス / 神経科学一般 / 神経・グリア相関

主な研究業績

Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease.

Ogawa Y, Sasanuma Y, Shitara S, Koshizuka A, Okada R, Sakuraba H, Oishi K.

Neuroscience Research. S0168-0102(19): 30120-8, 2019
Inhibition of astrocytic adenosine receptor A2A attenuates microglial activation in a mouse model of Sandhoff disease.

Ogawa Y, Furusawa E, Saitoh T, Sugimoto H, Omori T, Shimizu S, Kondo H, Yamazaki M, Sakuraba H, Oishi K.

Neurobiology of Disease. 118: 142-154. 2018
Improvement in dysmyelination by the inhibition of microglial activation in a mouse model of Sandhoff disease.

Ogawa Y, Irisa M, Sano T, Yanagi Y, Furusawa E, Saito T, Yamanaka S, Itoh K, Sakuraba H, Oishi K.

Neuroreport. 29 (11): 962-967. 2018
Abnormal differentiation of Sandhoff disease model mouse-derived multipotent stem cells toward a neural lineage.

Ogawa Y, Kaizu K, Yanagi Y, Takada S, Sakuraba H, Oishi K.

PLoS One. 12. e0178978. 2017
FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice.

Ogawa Y, Sano T, Irisa M, Kodama T, Saito T, Furusawa E, Kaizu K, Yanagi Y, Tsukimura T, Togawa T, Yamanaka S, Itoh K, Sakuraba H, Oishi K.

Scientific Reports. 7:40518, 2017
Induced Pluripotent Stem Cells Generated from P0-Cre;Z/EG Transgenic Mice.

Ogawa Y, Eto A, Miyake C, Tsuchida N, Miyake H, Takaku Y, Hagiwara H, Oishi K.

PLoS One. 18, e0138620, 2015.
Impaired neural differentiation of induced pluripotent stem cells generated from a mouse model of Sandhoff disease.

Ogawa Y, Tanaka M, Tanabe M, Suzuki T, Togawa T, Fukushige T, Kanekura T, Sakuraba H, Oishi K.

PLoS ONE, 8, e55856, 2013.
ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons.

Ogawa Y, Oses-Prieto J, Kim MY, Horresh I, Peles E, Burlingame AL, Trimmer JS, Meijer D, Rasband MN.

J Neurosci. 30, 1038-48, 2010.
Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.

Ogawa Y, Rasband MN.

J Neurosci Res. 87, 3502-10, 2009.
Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

Ogawa Y, Horresh I, Trimmer JS, Bredt DS, Peles E, Rasband MN.

J Neurosci. 28, 5731-9, 2008.
Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.

Ogawa Y, Schafer DP, Horresh I, Bar V, Hales K, Yang Y, Susuki K, Peles E, Stankewich MC, Rasband MN.

J Neurosci. 26, 5230-9, 2006.
Diversity of radial glial cells is formed along the dorso-ventral axis in the developing mouse spinal cord.

Ogawa Y, Takebayashi H, Takahashi M, Osumi N, Iwasaki Y, Ikenaka K.

Dev Neurosci. 27, 364-77, 2005.