研究

研究室

講師:飯田 克巳(イイダ カツミ)

研究室 基礎薬学部門/有機化学
最終学歴 明治薬科大学大学院薬学研究科博士課程(1990年3月)
学位 薬学博士(明治薬科大学: 1990年)
講義科目 化学演習、物理系薬学演習、地域医療コース特論
専門分野 天然物化学
研究課題 生合成研究
所属学会 日本薬学会
学内委員 体験学習委員会(2006-)、国家試験対策委員会(2012-)、実務実習委員会(2013-)
研究業績1 Evaluation of biosynthetic pathways to δ-aminolevulinic acid in Propionibacterium shermanii based on biosynthesis of vitamin B12 from D-[1-13C]glucose. Biochemistry 39, 3666-3670 (2000)
研究業績2 Evaluation of two biosynthetic pathways to δ-aminolevulinic acid in Euglena gracilis. Eur. J. Biochem. 269, 291-297 (2002)
研究業績3 Identification of tetrapyrrole compounds excreted by Rhodobacter sphaeroides and sources of the methyl hydrogens of bacteriochlorophyll a biosynthesized by R. sphaeroides, based on 13C-NMR spectral analysis of coproporphyrin III tetramethyl ester. Chem. Pharm. Bull. 55, 1067-1069 (2007)
研究業績4 Mechanism of the ring contraction process in vitamin B12 biosynthesis by the anaerobe Propionibacterium shermanii under aerobic conditions. FEBS J. 274, 3475-3481 (2007)
研究業績5 Metabolic pathways leading from amino acids to vitamin B12 in Propionibacterium shermanii, and the sources of the seven methyl carbons. FEBS J. 274, 5090-5095 (2007)
研究業績6 Efficient syntheses of benzyl and n-octyl [1,3-13C2]acetoacetates, and their application to syntheses of 13C-labelled pyrrole and 13C-labelled hymecromone. J. Label. Compd. Radiopharm. 51, 167-169 (2008)
研究業績7 Carbon source dependence of the ratio of δ-aminolevulinic acid biosynthesis via the C5 and Shemin pathways in Euglena gacilis (Euglenophyceae). J. Phycol. 44, 292-298 (2008)
研究業績8 Quantitative evaluation of the biosynthetic pathways leading to δ-aminolevulinic acid from the Shemin precursor glycine via the C5 pathway in Arthrobacter hyalinus by analysis of 13C-labeled coproporphyrinogen III biosynthesized from [2-13C]glycine, [1-13C]acetate, and [2-13C]acetate using 13C NMR spectroscopy. J. Radioanal. Nucl. Chem. 295, 1819-1827 (2013)
研究業績9 Investigation of the biosynthesis of acetyl-CoA and oxaloacetic acid from pyruvic acid and the quantitative evaluation of incorporated 13C-labeled L-alanine in Arthrobacter hyalinus. J. Radioanal. Nucl. Chem. 301, 897-904 (2014)
研究業績10 Investigation of acetyl-CoA and oxaloacetic acid biosynthesis from D-alanine-derived pyruvic acid in Arthrobacter hyalinus. J. Radioanal. Nucl. Chem. 304, 889-895 (2015)