助教:柳津 茂慧 (ヤナイヅ モトアキ)
役職名 |
助教 |
---|---|
研究室 | |
最終学歴 |
明治薬科大学大学院薬学研究科博士課程(後期)(2021年3月) |
学位 |
博士(薬科学)(明治薬科大学:2021年) |
講義科目 |
生命科学実習Ⅲ、薬の発見・発明 |
専門分野 |
分子生物学 |
研究課題 |
神経変性疾患に関連する遺伝子の発現制御機構の解明 |
所属学会 |
日本薬学会、日本分子生物学会、日本RNA学会 |
受賞歴 |
日本薬学会第139年会優秀発表賞(ポスター) |
研究業績1 |
Satoh J, Yanaizu M, Tosaki Y, Sakai K, Kino Y. Targeted sequencing approach to identify genetic mutations in Nasu-Hakola disease. Intractable Rare Dis. Res. 5(4), 269-274 (2016) doi: 10.5582/irdr.2016.01064 |
研究業績2 |
Satoh J, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Expression of gp91phox and p22phox, catalytic subunits of NADPH oxidase, on microglia in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 5(4), 275-279 (2016) doi: 10.5582/irdr.2016.01086 |
研究業績3 |
Satoh J, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Microglia express ABI3 in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 6(4), 262-268 (2017) doi: 10.5582/irdr.2017.01073 |
研究業績4 |
Satoh J, Yanaizu M, Tosaki Y, Sakai K, Kino Y, Ishida T, and Saito Y. Expression of GPR17, a regulator of oligodendrocyte differentiation and maturation, in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 6(1), 50-54 (2017) doi: 10.5582/irdr.2016.01097 |
研究業績5 |
Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express gamma-interferon-inducible lysosomal thiol reductase in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 7(4), 251-257 (2018) doi: 10.5582/irdr.2018.01119 |
研究業績6 |
Satoh J, Kino Y, Yanaizu M, Saito Y. Alzheimer's disease pathology in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 7(1), 32-36 (2018) doi: 10.5582/irdr.2017.01088 |
研究業績7 |
Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express TMEM119 in the brains of Nasu-Hakola disease. Intractable Rare Dis. Res. 8(4), 260-265 (2019) doi: 10.5582/irdr.2019.01123 |
研究業績8 |
Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express GPNMB in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 8(2), 120-128 (2019) doi: 10.5582/irdr.2019.01049 |
研究業績9 |
Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Reactive astrocytes express Aggregatin ( FAM222A) in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 9(4), 217-221 (2020) doi: 10.5582/irdr.2020.03080 |
研究業績10 |
Yanaizu M, Sakai K, Tosaki Y, Kino Y, Satoh J. Small nuclear RNA-mediated modulation of splicing reveals a therapeutic strategy for a TREM2 mutation and its post-transcriptional regulation. Scientific Reports. 8(1), 6937 (2018) doi: 10.1038/s41598-018-25204-2. |
研究業績11 |
Yanaizu M, Washizu C, Nukina N, Satoh J, Kino Y. CELF2 regulates the species-specific alternative splicing of TREM2. Scientific Reports. 10(1), 17995 (2020) doi: 10.1038/s41598-020-75057-x |
研究業績12 |
Komuro R, Honda Y, Yanaizu M, Nagahama M, Kino Y. Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins. Cells. 12(4), 602 (2023) doi: 10.3390/cells12040602. |
研究業績13 |
Yanaizu M, Adachi H, Araki M, Kontani K, Kino Y. Translational regulation and protein-coding capacity of the 5' untranslated region of human TREM2. Communications biology. 6(1), 616 (2023) doi: 10.1038/s42003-023-04998-6 |