研究

研究室

助教:柳津 茂慧 (ヤナイヅ モトアキ)

役職名

助教

研究室

病態RNA制御学

最終学歴

明治薬科大学大学院薬学研究科博士課程(後期)(2021年3月)

学位

博士(薬科学)(明治薬科大学:2021年)

講義科目

生命科学実習Ⅲ

専門分野

分子生物学

研究課題

神経変性疾患に関連する遺伝子の発現制御機構の解明

所属学会

日本薬学会、日本分子生物学会

受賞歴

日本薬学会第139年会優秀発表賞(ポスター)

研究業績1

Satoh J, Yanaizu M, Tosaki Y, Sakai K, Kino Y. Targeted sequencing approach to identify genetic mutations in Nasu-Hakola disease. Intractable Rare Dis. Res. 5(4), 269-274 (2016) doi: 10.5582/irdr.2016.01064

研究業績2

Satoh J, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Expression of gp91phox and p22phox, catalytic subunits of NADPH oxidase, on microglia in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 5(4), 275-279 (2016) doi: 10.5582/irdr.2016.01086

研究業績3

Satoh J, Kino Y, Yanaizu M, Tosaki Y, Sakai K, Ishida T, Saito Y. Microglia express ABI3 in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 6(4), 262-268 (2017) doi: 10.5582/irdr.2017.01073

研究業績4

Satoh J, Yanaizu M, Tosaki Y, Sakai K, Kino Y, Ishida T, and Saito Y. Expression of GPR17, a regulator of oligodendrocyte differentiation and maturation, in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 6(1), 50-54 (2017) doi: 10.5582/irdr.2016.01097

研究業績5

Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express gamma-interferon-inducible lysosomal thiol reductase in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 7(4), 251-257 (2018) doi: 10.5582/irdr.2018.01119

研究業績6

Satoh J, Kino Y, Yanaizu M, Saito Y. Alzheimer's disease pathology in Nasu-Hakola disease brains. Intractable Rare Dis. Res. 7(1), 32-36 (2018) doi: 10.5582/irdr.2017.01088

研究業績7

Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express TMEM119 in the brains of Nasu-Hakola disease. Intractable Rare Dis. Res. 8(4), 260-265 (2019) doi: 10.5582/irdr.2019.01123

研究業績8

Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Microglia express GPNMB in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 8(2), 120-128 (2019) doi: 10.5582/irdr.2019.01049

研究業績9

Satoh J, Kino Y, Yanaizu M, Ishida T, Saito Y. Reactive astrocytes express Aggregatin ( FAM222A) in the brains of Alzheimer's disease and Nasu-Hakola disease. Intractable Rare Dis. Res. 9(4), 217-221 (2020) doi: 10.5582/irdr.2020.03080

研究業績10

Yanaizu M, Sakai K, Tosaki Y, Kino Y, Satoh J. Small nuclear RNA-mediated modulation of splicing reveals a therapeutic strategy for a TREM2 mutation and its post-transcriptional regulation. Scientific Reports. 8(1), 6937 (2018) doi:

研究業績11

Yanaizu M, Washizu C, Nukina N, Satoh J, Kino Y. CELF2 regulates the species-specific alternative splicing of TREM2. Scientific Reports. 10(1), 17995 (2020) doi: 10.1038/s41598-020-75057-x