研究

研究室

助教:小田 絢子(オダ アヤコ)

研究室

薬剤情報解析学研究室

最終学歴

明治薬科大学薬学部薬学科(2016年3月)

学位

博士(薬学)(明治薬科大学:2024年)

担当科目

症例解析演習Ⅰ・Ⅱ、事前実務実習、病院薬学コース実習、病院薬学コース特論・演習

専門分野

医療薬学

研究課題

薬物療法の適正化に関する研究

所属学会

日本薬学会、日本医療薬学会、日本TDM学会、日本臨床薬理学会

受賞歴

第38回日本TDM学会・学術大会優秀演題賞(2022)

研究業績1

Evaluation of the usefulness of plasma 4β‐hydroxycholesterol concentration normalized by 4α‐hydroxycholesterol for accurate CYP3A phenotyping. Clin Transl Sci, 17(3), e13768 (2024)

研究業績2

Usefulness of Belimumab in Adult Patients With Systemic Lupus Erythematosus Evaluated Using Single Indexes: A Meta-Analysis and Systematic Review. Curr Ther Res Clin Exp, 100, 100738 (2024)

研究業績3

Relationship of plasma 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid concentration with OATP1B activity in patients with chronic kidney disease. Clin Transl Sci, 17(2), e13731 (2024)

研究業績4

Rapid and simple quantification of belimumab in human plasma using ultra-high performance liquid chromatography with tandem mass spectrometry. Clin Biochem, 124, 110706 (2024)

研究業績5

Evaluation of effects of indoxyl sulfate and parathyroid hormone on CYP3A activity considering the influence of CYP3A5 gene polymorphisms. Br J Clin Pharmacol, 89(12), 3648-3658 (2023).

研究業績6

Positive correlation between organic anion transporter 1B function indicated by plasma concentration of coproporphyrin-I and blood concentration of cyclosporin A in real-world patients. Br J Clin Pharmacol, 89(5), 1672-1681 (2023)

研究業績7

Highly sensitive simultaneous quantification of indoxyl sulfate and 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in human plasma using ultra-high performance liquid chromatography coupled with tandem mass spectrometry. J Sep Sci, 45(10), 1672-1682 (2022)

研究業績8

Sensitive UHPLC-MS/MS quantification method for 4β- and 4α-hydroxycholesterol in human plasma for accurate CYP3A phenotyping. J Lipid Res, 63(3), 100184 (2022)

研究業績9

Factors influencing plasma coproporphyrin-I concentration as biomarker of OATP1B activity in patients with rheumatoid arthritis. Clin Pharmacol Ther, 110(4), 1096-1105 (2021)

研究業績10

Relationship of hemoglobin level and plasma coproporphyrin-I concentrations as an endogenous probe for phenotyping OATP1. Clin Transl Sci, 14(4), 1403-1411 (2021)