研究

鈴木　陽介
(スズキ　ヨウスケ)

所属
薬剤情報解析学
職位
准教授
学位
博士（薬学）

研究キーワード

  • Precision dosing
  • 質量分析
  • バイオマーカー

研究分野

  • 医療薬学、分析化学、予防薬学

主な研究業績

  • Discovery of novel plasma biomarkers for OATP1B1 activity using nontargeted metabolomics.

    Negami J, Suzuki Y, Koyama T, Oda A, Iino K, Suzuki S, Yamagishi N, Kamio N, Ozaki E, Yamamoto Y, Nakatochi M, Momozawa Y, Tanaka R, Ono H, Sumimoto T, Tatsuta R, Itoh H, Takashima N, Matsuo K, Ohno K.

    Drug Metab Dispos, 54, 100366 (2026)

  • Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort.

    Tanaka R, Suzuki Y, Koyama T, Sumimoto T, Oda A, Sato H, Ozaki E, Tatsuta R, Yamamoto Y, Nakatochi M, Momozawa Y, Ohno K, Takashima N, Matsuo K, Itoh H.

    Eur J Clin Pharmacol, 82, 180 (2026)

  • Plasma Mid-Regional Pro-adrenomedullin as a Prognostic Biomarker in Hematopoietic Stem Cell Transplant Recipients with Febrile Neutropenia.

    Iwao M, Tanaka R, Shiraiwa K, Sueshige Y, Suzuki Y, Takano K, Tatsuta R, Ogata M, Itoh H.

    Biol Pharm Bull, 49, 785-793 (2026)

  • Plasma coproporphyrins for evaluating OATP1B and OATP2B1 activities: Coproporphyrin-III unsuitable as an OATP2B1 biomarker in Japanese general population.

    Negami J, Suzuki Y, Koyama T, Yamazaki M, Oda A, Ozaki E, Yamamoto Y, Nakatochi M, Momozawa Y, Takashima N, Matsuo K, Ohno K.

    Drug Metab Dispos, 54, 100276 (2026)

  • Post‑transplant trajectories and renal function associations of mid‑regional pro‑adrenomedullin, mid‑regional pro‑atrial natriuretic peptide, and copeptin in kidney transplant recipients.

    Iwao M, Tanaka R, Suzuki Y, Oda A, Ono H, Tatsuta R, Ando T, Shin T, Ohno K, Itoh H.

    Peptides, 197, 171484 (2026)

  • Ultra-Sensitive Quantification of Indoxyl Sulfate and 3-Carboxy-4-Methyl-5-Propyl-2-Furanpropanoic Acid in Plasma Using Ultra-Performance Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry.

    Negami J, Suzuki Y, Sato H, Toyama D, Oda A, Tanaka R, Ono H, Ando T, Shin T, Itoh H, Ohno K.

    J Clin Lab Anal, 39, e70077 (2025)

  • Ultra-sensitive quantification of mid-regional proadrenomedullin in human plasma using micro-liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.

    Suzuki Y, Koyama T, Negami J, Toyama D, Oda A, Tanaka R, Iwao M, Tatsuta R, Ando T, Shin T, Itoh H, Ohno K.

    ACS Omega, 10, 24214-24223 (2025)

  • Impact of Cancer Cachexia Progression on OATP1B1 Transport Activity: Quantitative Analysis Using Coproporphyrin-I as an Endogenous Biomarker.

    Sumimoto T, Tanaka R, Suzuki Y, Negami J, Sueshige Y, Oda A, Shiraiwa K, Inagaki T, Nishikawa K, Tatsuta R, Otsu S, Ogata M, Ohno K, Itoh H.

    Clin Pharmacol Ther, 118, 128-137 (2025)

  • The active metabolite hydroxyitraconazole has substantially higher in vivo free fraction and free concentrations compared to itraconazole.

    Iwao M, Tanaka R, Suzuki Y, Tatsuta R, Hashimoto T, Hiramatsu K, Itoh H.

    J Pharm Biomed Anal, 259, 116775 (2025)

  • Ultra-Sensitive Quantification of Coproporphyrin-I and -III in Human Plasma Using Ultra-Performance Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry.

    Negami J, Suzuki Y, Sato H, Toyama D, Tanaka R, Ono H, Oda A, Tatsuta R, Ozaki T, Shibata H, Itoh H, Ohno K.

    ACS Omega, 9, 47135-47144 (2024)

所属学協会

  • 日本薬学会、日本医療薬学会、日本TDM学会、日本臨床薬理学会、日本化学療法学会

研究者情報の詳細は
researchmap をご覧ください。

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