研究

研究室

講師:永井 純子(ナガイ ジュンコ)

研究室

IR室

(IR; Institutional Research / インスティテューショナル・リサーチ)

 IR室ホームページはこちら

researchmap

researchmap

最終学歴

明治薬科大学大学院薬学研究科薬学専攻博士課程 (2018年3月)

学位

博士(薬学) (明治薬科大学: 2018年)

講義科目

医療面接入門、症例解析演習Ⅰ・Ⅱ、事前実務実習、病院薬学コース特論・演習、薬物治療学Ⅴ

学内委員

学内実習委員会(事前実務実習部門)、OSCE実施委員会、女子寮せせらぎ管理運営委員会、学生厚生委員会

社会活動
  • 2019年度第6回関東地区調整機構 認定実務実習指導薬剤師のためのアドバンストワークショップ タスクフォース
  • 平成30年度第12回関東地区調整機構 認定実務実習指導薬剤師のためのアドバンストワークショップ タスクフォース
  • 明薬会(明治薬科大学同窓会)理事:学術企画部
  • 紀尾井会(明治薬科大学卒の女性薬剤師を中心とした会)役員:研修係

所属学会
  • 日本薬学教育学会
  • 大学評価コンソーシアム
  • 日本インスティテューショナル・リサーチ協会
  • International Society for Pharmacoepidemiology
  • 日本薬剤疫学会
  • 日本薬学会
  • 日本医療薬学会
  • 日本緩和医療学会
依頼講演

CBI学会2017年大会「医薬品の副作用データに基づく定量的構造活性相関」 (東京, 2017)

受賞歴

平成27年度全国済生会病院薬剤師会優秀論文賞 (2016)

研究業績1

Nagai J, Ishikawa Y. Analysis of anticholinergic adverse effects using two large databases: The US Food and Drug Administration Adverse Event Reporting System database and the Japanese Adverse Drug Event Report database. PLoS One. 2021;16(12):e0260980. doi: 10.1371/journal.pone.0260980. eCollection 2021. PubMed PMID: 34855908; PubMed Central PMCID: PMC8638968.

研究業績2
Takao K, Takemura Y, Nagai J, Kamauchi H, Hoshi K, Mabashi R, Uesawa Y, Sugita Y. Synthesis and biological evaluation of 3-styrylchromone derivatives as selective monoamine oxidase B inhibitors. Bioorg Med Chem. 2021 Jul 15;42:116255. doi: 10.1016/j.bmc.2021.116255. Epub 2021 Jun 5. PubMed PMID: 34119696.
研究業績3

Kan Y, Nagai J, Uesawa Y. Evaluation of antibiotic-induced taste and smell disorders using the FDA adverse event reporting system database. Sci Rep. 2021 May 5;11(1):9625. doi: 10.1038/s41598-021-88958-2. PubMed PMID: 33953272; PubMed Central PMCID: PMC8100100.

研究業績4

Teratani M, Nakamura S, Sakagami H, Fujise M, Hashimoto M, Okudaira N, Bandow K, Iijima Y, Nagai J, Uesawa Y, Wakabayashi H. Antitumor Effects and Tumor-specificity of Guaiazulene-3-Carboxylate Derivatives Against Oral Squamous Cell Carcinoma In Vitro. Anticancer Res. 2020 Sep;40(9):4885-4894. doi: 10.21873/anticanres.14491. PubMed PMID: 32878776.

研究業績5
Sugita Y, Takao K, Uesawa Y, Nagai J, Iijima Y, Sano M, Sakagami H. Development of Newly Synthesized Chromone Derivatives with High Tumor Specificity against Human Oral Squamous Cell Carcinoma. Medicines (Basel). 2020 Aug 26;7(9). doi: 10.3390/medicines7090050. Review. PubMed PMID: 32858984; PubMed Central PMCID: PMC7555025.
研究業績6

Usami Y, Higuchi M, Mizuki K, Yamamoto M, Kanki M, Nakasone C, Sugimoto Y, Shibano M, Uesawa Y, Nagai J, Yoneyama H, Harusawa S. Syntheses and Glycosidase Inhibitory Activities, and in Silico Docking Studies of Pericosine E Analogs Methoxy-Substituted at C6. Mar Drugs. 2020 Apr 20;18(4). doi: 10.3390/md18040221. PubMed PMID: 32326065; PubMed Central PMCID: PMC7230162.

研究業績7

Takao K, Hoshi K, Sakagami H, Shi H, Bandow K, Nagai J, Uesawa Y, Tomomura A, Tomomura M, Sugita Y. Further Quantitative Structure-Cytotoxicity Relationship Analysis of 3-Styrylchromones. Anticancer Res. 2020 Jan;40(1):87-95. doi: 10.21873/anticanres.13929. PubMed PMID: 31892556.

研究業績8

Nagai J, Shi H, Sezaki N, Yoshida N, Bandow K, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y. Quantitative Structure-Cytotoxicity Relationship of 2-Arylazolylchromones and 2-Triazolylchromones. Anticancer Res. 2019 Dec;39(12):6479-6488. doi: 10.21873/anticanres.13862. PubMed PMID: 31810912.

研究業績9

Uesawa Y, Nagai J, Shi H, Sakagami H, Bandow K, Tomomura A, Tomomura M, Endo S, Takao K, Sugita Y. Quantitative Structure-Cytotoxicity Relationship of 2-Styrylchromones. Anticancer Res. 2019 Dec;39(12):6489-6498. doi: 10.21873/anticanres.13863. PubMed PMID: 31810913.

研究業績10

Takao K, Endo S, Nagai J, Kamauchi H, Takemura Y, Uesawa Y, Sugita Y. 2-Styrylchromone derivatives as potent and selective monoamine oxidase B inhibitors. Bioorg Chem. 2019 Nov;92:103285. doi: 10.1016/j.bioorg.2019.103285. Epub 2019 Sep 18. PubMed PMID: 31561103.

研究業績11

Imanari K, Hashimoto M, Wakabayashi H, Okudaira N, Bandow K, Nagai J, Tomomura M, Tomomura A, Uesawa Y, Sakagami H. Quantitative Structure-Cytotoxicity Relationship of Azulene Amide Derivatives. Anticancer Res. 2019 Jul;39(7):3507-3518. doi: 10.21873/anticanres.13497. PubMed PMID: 31262875.

研究業績12

Nagai J, Imamura M, Sakagami H, Uesawa Y. QSAR Prediction Model to Search for Compounds with Selective Cytotoxicity Against Oral Cell Cancer. Medicines (Basel). 2019 Apr 1;6(2). doi: 10.3390/medicines6020045. PubMed PMID: 30939759; PubMed Central PMCID: PMC6631777.

研究業績13

Sakagami H, Watanabe T, Hoshino T, Suda N, Mori K, Yasui T, Yamauchi N, Kashiwagi H, Gomi T, Oizumi T, Nagai J, Uesawa Y, Takao K, Sugita Y. Recent Progress of Basic Studies of Natural Products and Their Dental Application. Medicines (Basel). 2018 Dec 25;6(1). doi: 10.3390/medicines6010004. Review. PubMed PMID: 30585249; PubMed Central PMCID: PMC6473826.

研究業績14

Nagai J, Shi H, Kubota Y, Bandow K, Okudaira N, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y. Quantitative Structure-Cytotoxicity Relationship of Pyrano[4,3-b]chromones. Anticancer Res. 2018 Aug;38(8):4449-4457. doi: 10.21873/anticanres.12747. PubMed PMID: 30061209.

研究業績15

Shi H, Nagai J, Sakatsume T, Bandow K, Okudaira N, Uesawa Y, Sakagami H, Tomomura M, Tomomura A, Takao K, Sugita Y. Quantitative Structure-Cytotoxicity Relationship of 3-(N-Cyclicamino)chromone Derivatives. Anticancer Res. 2018 Aug;38(8):4459-4467. doi: 10.21873/anticanres.12748. PubMed PMID: 30061210.

研究業績16

Shi H, Nagai J, Sakatsume T, Bandow K, Okudaira N, Sakagami H, Tomomura M, Tomomura A, Uesawa Y, Takao K, Sugita Y. Quantitative Structure-Cytotoxicity Relationship of 2-(N-cyclicamino)chromone Derivatives. Anticancer Res. 2018 Jul;38(7):3897-3906. doi: 10.21873/anticanres.12674. PubMed PMID: 29970510.

研究業績17

Nagai J, Kagaya H, Uesawa Y. Analysis of physicochemical properties of drugs included in anticholinergic rating scales. Chem-Bio Informatics Journal. 2018 January; 18:1-9. doi: https://doi.org/10.1273/cbij.18.1.

研究業績18

Nagai J, Uesawa Y, Shimamura R, Kagaya H. Characterization of the Adverse Effects Induced by Acetaminophen and Nonsteroidal Anti-Inflammatory Drugs Based on the Analysis of the Japanese Adverse Drug Event Report Database. Clin J Pain. 2017 Aug;33(8):667-675. doi: 10.1097/AJP.0000000000000457. PubMed PMID: 27898459; PubMed Central PMCID: PMC5497783.

研究業績19

Nagai J, Uesawa Y, Kagaya H. Analyses of oxycodone-induced adverse effects based on the Japanese Adverse Drug Event Report Database. Palliative Care Research. 2015 May; 10(3):161-168. doi: https://doi.org/10.2512/jspm.10.161.

研究業績20

Nagai J, Uesawa Y, Kagaya H. Analyses of opioid-induced adverse effects based on Japanese Adverse Drug Event Report database:Distinctive tendencies of the adverse events induced by morphine, fentanyl and oxycodone. Palliative Care Research. 2014 November; 10(1):113-119. doi: https://doi.org/10.2512/jspm.10.113.