講師：伊藤　元気（イトウ　モトキ）

機能分子化学

大阪大学大学院薬学研究科博士後期課程（2011年3月）

博士（薬学）（大阪大学：2011年）

物理化学II、錯体化学、薬の科学実習Ⅲ－２

有機合成化学

日本薬学会、有機合成化学協会

2017年 有機合成化学協会 富士フィルム研究企画賞

2024年 日本薬学会関東支部奨励賞

Functionalization of Siloxanes with Arynes Generated from o-Triazenylarylboronic Acids
Motoki Ito, Ryuhei Oda, Akari Shoji, Kazuhiro Higuchi, Shigeo Sugiyama
Chem. Pharm. Bull. 2024, 72, 487－497. DOI: 10.1248/cpb.c24-00192.

Development of 3-triazenylaryne and its application to iterative aryne reactions via o-triazenylarylboronic acids
Motoki Ito, Yuta Takishima, Rinto Ishikawa, Mao Kamumura, Hana Watanabe, Takehiro Konishi, Kazuhiro Higuchi, Shigeo Sugiyama
Chem. Commun 2023, 59, 14249-14252. DOI: 10.1039/D3CC04878K.

An Improved Procedure for Aryne Generation from o-Triazenylarylboronic Acids through One-Pot Boronate Formation/Silica Gel Treatment
Motoki Ito, Haruna Yamazaki, Aguri Ito, Ryuhei Oda, Moeka Komiya, Kazuhiro Higuchi, Shigeo Sugiyama
Eur. J. Org. Chem. 2023, 26, e202300458. DOI: 10.1002/ejoc.202300458.

Dirhodium(II)-Catalyzed Synthesis of N-(Arylsulfonyl)hydrazines by N–H Amination of Aliphatic Amines

Motoki Ito, Yui Hasegawa, Satomi Saito, Asami Onda, Kazuhiro Higuchi, Shigeo Sugiyama

Synlett 2022, 33, 367－370. DOI: 10.1055/s-0041-1737759.

Aryne Generation from o-Triazenylarylboronic Acids Induced by Brønsted Acid
Motoki Ito, Yuka Yamabayashi, Yuta Takishima, Kazuhiro Higuchi, Shigeo Sugiyama, S.
Chem. Pharm. Bull. 2022, 70, 566－572. DOI: 10.1248/cpb.c22-00264.

Silica gel-induced aryne generation from o-triazenylarylboronic acids as stable solid precursors

Motoki Ito, Yuka Yamabayashi, Mio Oikawa, Emi Kano, Kazuhiro Higuchi, Shigeo Sugiyama

Org. Chem. Front. 2021, 8, 2963－2969. DOI: 10.1039/D1QO00385B.

Dirhodium(II)-Catalyzed ortho C–H Amination of N-Alkyldiarylamines

Motoki Ito, Mamiko Mori, Tomoya Nakagawa, Miki Hori, Kazuhiro Higuchi, Shigeo Sugiyama

Heterocycles 2021, 103, 403－415. DOI: 10.3987/COM-20-S(K)27.

One-pot generation of benzynes from 2-aminophenylboronates via a Rh(II)-catalyzed N–H amination/oxidation/elimination cascade process
Ito, M.;Tanaka, A.; Hatakeyama, K.; Kano, E.; Higuchi, K.; Sugiyama, S.
Org. Chem. Front. 2020, 7, 64－68. DOI: 10.1039/C9QO01115C.

Dirhodium(II)-Catalyzed ortho C−H Amination of Sterically Congested N,N-Dialkylanilines

Motoki Ito, Tomoya Nakagawa, Kazuhiro Higuchi, Shigeo Sugiyama

Org. Biomol. Chem. 2018, 16, 6876-6881. DOI: 10.1039/C8OB01974F.

Rhodium(II)-Catalyzed Synthesis of N-Aryl-N′-tosyldiazenes from Primary Aromatic Amines Using (Tosylimino)aryliodinane: A Potent Stable Surrogate for Diazonium Salts

Motoki Ito, Arisa Tanaka, Kazuhiro Higuchi, Shigeo Sugiyama

Eur. J. Org. Chem. 2017, 1272-1276. DOI: 10.1002/ejoc.201601627.