Highly Diastereoselective Claisen Rearrangement Leading to Vicinal Quaternary Carbons Construction of Oxindoles Matsuta Y., Kobari T., Kurashima S., Kumakura Y., Shinada M., Higuchi K., Kawasaki T. Tetrahedron Lett., 52, 6199-6202 (2011)

Active Thionium Species Mediated Functionalization at the 2α-position of Indole Derivatives Higuchi K., Tayu M., Kawasaki T. Chem. Commun., 47, 6728-6730 (2011)

Reductive Cyclization of 3-Cyanomethyloxindoles to Hexahydro-2-oxopyrrolo[2,3- b]indoles with Lithium Aluminum Hydride Shinada M., Aihara Y., Takiguchi S., Ban N., Higuchi K., Kawasaki T. Heterocycles, 82, 631-639 (2010)

Claisen Rearrangement through Enolization of 2-Allyloxyindolin-3-ones: Construction of Adjacent Carbon Stereocenters in 3-Hydroxyindolin-2-ones Higuchi K., Saito K., Hirayama T., Watanabe Y., Kobayashi E., Kawasaki T. Synthesis 3609-3614 (2010)

First Total Synthesis and Stereochemical Revision of Okaramine M Iizuka T., Takiguchi S., Kumakura Y., Tsukioka N., Higuchi K., Kawasaki T. Tetrahedron Lett. 51, 6003-6005 (2010)

Total Syntheses of (-)-Fructigenine A and (-)-5-N-Acetylardeemin Takiguchi S., Iizuka T., Kumakura Y., Murasaki K., Ban N., Higuchi K., Kawasaki T. J. Org. Chem. 75, 1126-1131 (2010)

Preparation of 2,2-Disubstituted 1,2-Dihydro-3H-indol-3-ones via Oxidation of 2-Substituted Indoles and Mannich-type Reaction Higuchi K, Sato Y, KojimaS, Tsuchimochi M, Sugiura K, Hatori M, Kawasaki T Tetrahedron 66, 1236-1243 (2010)

Synthesis of 1,2,4-Triazin-5-ones through [4+2] Cycloaddition of 1,2,4-Triaza-1,3-dienes with Diphenylketene T. Nakai, K. Fukutomi, H. Yanagisawa, T. Kawasaki, and M. Sakamoto Heterocycles, 79, 627-633 (2009)

First Total Synthesis of Hinckdentine A K. Higuchi, Y. Sato, M. Tsuchimochi, K, Sugiura, M. Hatori and T. Kawasaki Org. Lett., 11, 197-199 (2009)

Total Synthesis of (±)-Flustramines A and C, (±)-Flustramide A,and (-)- and (+)-Debromoflustramines A T. Kawasaki, M. Shinada, M. Ohzono, A. Ogawa, R. Terashima, M. Sakamoto J. Org. Chem., 73, 5959-5964 (2008).

Synthesis of the Benzo-fused Indolizidine Alkaloid mimics. Comins D. L, Higuchi K Beilstein J. Org. Chem. 3, 42 (2007).

Asymmetric Alkylation of 2-Monosubstituted Indolin-3-ones, K. Higuchi, K. Masuda, T. Koseki, M. Hatori, M. Sakamoto, T. Kawasaki Heterocycles, 73, 641-650 (2007).

Total Synthesis of Marine Bisindole Alkaloid, (+)-cis-Dihydrohamacanthin B K. Higuchi, R. Takei, T. Kouko, T. Kawasaki Synthesis, 2007, 669-674.

Silyl-Enolization-Asymmetric Claisen Rearrangement of 2-Allyloxyindolin-3-one: Enantioselective Total Synthesis of 3a-Hydroxypyrrolo[2,3-b]indoline Alkaloid Alline, T. Kawasaki, W. Takamiya, N. Okamoto, M. Nagaoka, T. Hirayama Tetrahedron Lett., 47, 5379-5382 (2006).

Enantioselective total synthesis of (-)-flustramines A, B and (-)-flustramides A, B via domino olefination/isomerization/Claisen rearrangement sequence T. Kawasaki, M. Shinada, D. Kamimura, M. Ohzono, A. Ogawa Chem. Commun. 420-422 (2006)

Synthesis of Diversely Functionalized Hexahydropyrrolo[2,3-b]indoles Using Domino Reactions, Olefination, Isomerization and Claisen Rearrangement Followed by Reductive Cyclization T. Kawasaki, A. Ogawa, R. Terashima, T. Saheki, N. Ban, H. Sekiguchi, K. Sakaguchi, M. Sakamoto　 J. Org. Chem., 70, 2957-2966 (2005).

Total Synthesis of Marine Bisindole Alkaloids, (+)-Hamacanthins A, B and (-)-Antipode of cis-Dihydrohamacanthin B T. Kouko, K. Matsumura, T. Kawasaki, Tetrahedron, 61, 2309-2318 (2005)

Novel Synthesis of Optically Pure Indolylglycinols Using Lipase-Mediated Resolution T. Kouko, J. Kobayashi, A. Ohta, M. Sakamoto, T. Kawasaki,　 Synthesis, 2463-2470 (2004).

Synthesis of 3-hydroxyindolin-2-one alkaloids, (±)-donaxaridine and (±)-convolutamydines A and E, through enolization-Claisen rearrangement of 2-allyloxyindolin-3-ones T. Kawasaki, M. Nagaoka, T. Satoh, A. Okamoto, R. Ukon., A. Ogawa, Tetrahedron, 60, 3493-3503 (2004).

Synthesis of Marine Bisindole Alkaloids, Hamacanthins A and B through Intramolecular Transamidation-Cyclization T. Kawasaki, T. Kouko, H. Totsuka, K. Hiramatsu, Tetrahedron Lett., 44, 8849-8852 (2003).

Enantioselective Total Synthesis of (-)-Pseudophrynaminol through Tandem Olefination, Isomerization and Asymmetric Claisen Rearrangement T. Kawasaki, A. Ogawa, Y. Takashima, M. Sakamoto, Tetrahedron Lett., 44, 1591-1593 (2003).

Syntheses of Bis(indolyl)piperazine Alkaloids, Dragmacidin B and C, and Dihydrohamacanthin A T. Kawasaki, K. Ohno, H. Enoki, Y. Umemoto, M. Sakamoto, Tetrahedron Lett., 43, 4245-4248 (2002).

Reverse Aromatic Cope Rearrangement of 2-Allyl-3-alkylideneindolines driven by Olefination of 2-Allylindolin-3-ones: Synthesis of a-Allyl-3-indole Acetate Derivatives T. Kawasaki, Y. Nonaka, K. Watanabe, A. Ogawa, K. Higuchi, R. Terashima, K. Masuda, M. Sakamoto, J. Org. Chem., 66, 1200-1204 (2001).

Stereocontrolled Synthesis of Multi-functionalized β-Substituted α-Amino Acids: Nitrone Cycloaddition Approach O. Tamura, S. Yoshida, H. Sugita, N. Mita, Y. Uyama, N. Morita, M. Ishiguro, T. Kawasaki, H. Ishibashi, M. Sakamoto, Synlett, 1553-1556 (2000).

First Total Synthesis of Dragmacidin A via Indolylglycines T. Kawasaki, H. Enoki, K. Matsumura, M. Ohyama, M. Inagawa, M. Sakamoto, Org. Lett., 2, 3027-3029 (2000)

Total Synthesis of Antioxidant Alkaloid Carazostatin via Electrocyclic Ring Closure of 3-Butadienyl-2-methoxyindole, Y. Nonaka, T. Kawasaki, M. Sakamoto, Heterocycles, 53, 1681-1684 (2000).

An Efficient Synthetic Method for 2-Methoxy-1,2-dihydro-3H-indol-3-ones, T. Kawasaki, Y. Nonaka, K. Matsumura, M. Monai, M. Sakamoto, Synth. Commun., 29, 3251-3261 (1999).

Michael additions of 1,2-dihydro-3H-indol-3-ones and some reactions of Michael adducts with ammonium acetate, T. Kawasaki, C.-Y. Tang, H. Nakanishi, S. Hirai, T. Ohshita, M. Tanizawa, M. Himori, H. Satoh, M. Sakamoto, K. Miura, F. Nakano, J. Chem. Soc., Perkin Trans. 1, 327-333 (1999)

Addition-Cyclization of 2-Hydroxy-2,3-dihydroindol-3-ones with Acetylenecarboxylate: Preparation of Furo[2,3-b]indoles, T. Kawasaki, C.-Y. Tang , E. Koizumi, H. Nakanishi, M. Sakamoto, Heterocycles, 48, 975-980 (1998).

Reactions of Diazoalkanes with Molybdenum Peroxide, T. Kawasaki, R. Hoshi, T. Yamamoto, K. Satoh, M. Sakamoto, Acta Chim. Hung.-Models in Chem., 135, 565-572 (1998).

Synthesis of 4-(2-Aminoethyl)indoles through Claisen Ortho-Amide Rearrangement of 3-Hydroxy-2-methoxyindolines, T. Kawasaki, H. Ohtsuka, A. Mihira, M. Sakamoto, Heterocycles, 47, 367-373 (1998).

Unusual Cyclization and SN'-Type Displacement of Carbazole Sulfoxide under Pummerer Reaction Conditions, T. Kawasaki, H. Suzuki, I. Sakata, H. Nakanishi, M. Sakamoto, Tetrahedron Lett., 38, 3251-3252 (1997).

A Short Route to "Reverse-Prenylated" Pyrrolo[2,3-b]indoles via Tandem Olefination and Claisen Rearrangement of 2-(3,3-Dimethylallyloxy)indol-3-ones: First Total Synthesis of Flustramine C, T. Kawasaki, R. Terashima, K. Sakaguchi, H. Sekiguchi, M. Sakamoto, Tetrahedron Lett., 37, 7525-7528 (1996).

Synthesis of 1,2-Dihydro-2-allylindol-3-ones using in situ Claisen Rearrangement of 1,2-Dihydroindol-3-ones with Allyl Alcohols, T. Kawasaki, K. Masuda, Y. Baba, R. Terashima, K. Takada, M. Sakamoto, J. Chem. Soc., Perkin Trans. 1, 729-733 (1996).

Tandem Wittig Reaction and Cope Rearrangement of 2-Allyl-1,2-dihydroindol-3-ones to 3-Indole Acetates, T. Kawasaki, K. Watanabe, K. Masuda, M. Sakamoto, J. Chem. Soc., Chem. Commun., 381-382 (1995).

総説と著書

立体選択的第四級炭素構築反応とピロリジノ[2,3-b]インドリン系天然物合成への応用 川�ｱ知己 有機合成化学協会誌 67, 1012-1024 (2009).

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit, K. Higuchi, T. Kawasaki Nat. Prod. Rep., 24, 843-868 (2007).

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit T. Kawasaki and K. Higuchi Nat. Prod. Rep., 22, 761- 93 (2005).

Diethyl Cyanomethylphosphonate. T. Kawasaki e-EROS Encyclopedia of Reagents for Organic Synthesis, (2008), John Wiley & Sons, http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554785/HOME.

生物活性海洋天然物ビスインドールピラジン 川崎知己 明治薬科大学研究紀要, 33, 13-30 (2003).

ペリ環状反応の化学とその複素環化合物合成への応用 坂本正徳、川崎知己、石井啓太郎、田村修 薬学雑誌, 123, 717-759 (2003).

薬学教育研究会編、CBT対策と演習　有機化学、2008（廣川書店） 川崎知己、第1章（pp. 1-47）

野上靖純、田口武夫、長　普子編、パートナー薬品製造学　第2版、2012 (南江堂) 坂本正徳、川�ｱ知己、第3章 (pp. 93-124).

小林　進、三巻祥浩編、基礎有機化学、2012 (培風館) 川�ｱ知己、第2章(pp. 13-22).

有機合成化学協会編、天然物の全合成で活躍した反応　実験のコツとポイント (日本)、2011(化学同人) 川�ｱ知己、pp. 142-143, 178-179.

有機合成化学協会編、天然物の全合成　2000〜2008 (日本)、2009(化学同人) 川�ｱ知己、pp. 70-71.

日本薬学会編、スタンダード薬学シリーズ３　化学系薬学　�W. 演習編、2007（東京化学同人） 川崎知己、pp. 90-99、pp. 179-190.

長野哲雄、夏苅英昭、原　博編、創薬化学、2004（東京化学同人） 川崎知己、pp. 17-19、pp. 46-56、pp. 89-94、pp. 99-105、pp. 114-116.

栗原拓史、内藤猛章編、有機薬品製造化学　第４版、2004（廣川書店） 川崎知己、第1章 (pp. 9-38).

北　泰行、平岡哲雄編、創薬化学?有機化学からのアプローチ?、2004（東京化学同人） 川崎知己、pp. 41-63.

梶原正宏、坂本正徳、川崎知己、プログラム学習 有機合成問題の解き方：2001（東京化学同人） 川崎知己、、pp. 121-159, 186-206.