文献ストーレッジ(要パスワード）
大学紀要：2006/7, 2008,2009, 2010、2011  2012
2012MBI紀要  医療の歴史
書籍
1. 石橋賢一：腎臓におけるリン排泄機構とその制御。鈴木正司、秋澤忠男（編）腎不全とリン　45-50頁。日本メディカルセンター、東京、2004.
2. 石橋賢一、森下義幸：アクアポリンスーパーファミリー。Annual Review腎臓2005、中外医学社34-39
3. 石橋賢一：アクアポリンの仲間たち。第１９回「大学と科学」公開シンポジウム。みずみずしい体のしくみ：水の通り道「アクアポリン」の働きと病気。p10-18, クバクロ、東京、2005.
4.水とアクアポリンの生物学。佐々木成（編）中山書店　2008

5. からだと水の事典。佐々木成，石橋賢一（編）　朝倉書店　２００８

学会発表

Kobayashi K, Ishibashi K, Sasaki S. Neonatalkidney of AQP11-disrupted mice

exhibit ER stress-induced apoptosis of theproximal tubules followed by a remarkable slowing of cyst-formation byrapamycin treatment. ASN 2007, San Francisco

Ishibashi K. Tissue distributions of two-porechannel family (TPCN). ASN 2007, San Francisco
吉永一也、近藤慎一、今泉和則、石橋賢一：アクアポリン欠損マウスにみられた精巣内アポトーシス。日本解剖学会63回九州支部学術総会、２００７，１０、長崎

小林克樹、石橋賢一、佐々木成：AQP11ノックアウトマウスののう胞形成におけるアポトーシスの役割。日本腎臓学会50回総会、２００７、５．浜松

安西尚彦、加国雅和、大房健、石橋賢一、吉里勝利、遠藤仁：ヒト肝細胞キメラマウスにおけるヒトアルブミン値と血清尿酸値の相関性に関する検討。日本 腎臓学会50回総会、２００７、５．浜松
石橋賢一、小林克樹、佐々木成：水チャネルAQP-1/AQP-11ダブルノックアウトマウスの腎病変。日本腎臓学会50回総会、２００７、５．浜松
石橋賢一：アクアポリン研究の新展開。教育講演―Ａ。日本腎臓学会37回東部学術大会、２００７、１０．大宮
Ishibashi K: Subcellular aquaporins: New andold memebers. 5th International Conference of Aquaporin. 2007. 7, Nara

Okada S, Ishibashi K, Kobayashi K, MatsumotoI, Misaka T, Abe K.: Microarray analysis of the kidney with vacuolized proximaltubules from AQP11 knockout mouse. 5th International Conference ofAquaporin. 2007. 7, Nara

Kobayashi K, Ishibashi K, Sasaki S. Neonatalkidney of AQP11-disrupted mice exhibit ER stress-induced apoptosis of theproximal tubules followed by a remarkable slowing of cyst-formation byrapamycin treatment. 5th International Conference of Aquaporin.2007. 7, Nara

Yakata K, Hiroaki Y, Ishibashi K, Sohara E,Sasaki S, Mitsuoka K, Fujiyoshi Y.: Functional analysis of aquaporin-11 both inpure phospholipid membrane and in insect cell membrane. 5thInternational Conference of Aquaporin. 2007. 7, Nara

Kawada H, Yasuoka Y, Fukuda H, Ishibashi K,Kawahara K.: Expression of aquaporin-1 in a newly established cell line ofmouse macula densa. 5th International Conference of Aquaporin. 2007. Nara

岡田 晋治、三坂 巧、松本 一朗、石橋 賢一、阿部 啓子:アクアポリン11KOマウスにおけるのう胞腎形成機構の解析日本農芸学会２００８．３名古屋

招待講演
1. Symposium: The role of AQP11 in intracellular organelle homeostasis: Ishibashi K, The 11th International Symposium on Exocrine Secretion (ISES), Tokushima09, 2009/7, Tokushima
2. Symposium: The physiological roles of subcellular aquaporins: Ishibashi K, 36th International Congress of Physiological Sciences, 2009/8, Kyoto
一般講演・ポスター発表
1. Pancreas-specific aquaporin12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis: Ohta Ea, Itoh Ta, Nemoto Tb, Kumagai J, Ko SBc, Ishibashi K, Ohno Md, Uchida Kd, Ohta Aa, Sohara Ea, Uchida Sa, Sasaki Sa, Rai Ta (aDepartment of Nephrology and Department of Pathology, Tokyo Medical and Dental University, ｂSupportive Center for Brain Research, National Institute for Physiological Sciences and Japan Science and Technology Agency, Core Research for Evolutional Science and Technology, cDivision of Gastroenterology, Department of Medicine, Nagoya University Graduate School of Medicine, dDepartment of Medicine, Kidney Center, Tokyo Women's Medical University), 36th International Congress of Physiological Sciences, 2009/8, Kyoto
2. The role of AQP11 in intracellular organelles: Tanaka Y, Hirokawa T, Kondo S, Hara S, Ishibashi K, 36th International Congress of Physiological Sciences, 2009/8, Kyoto, Japan
3. Loss of Aquaporin-11 Causes Both the Apoptosis and the Enhanced Cell Proliferation of the Renal Proximal Tubule Cells: Kobayashi Ka, Shinada Eb, Ishibashi K, Uchida Sb, Sasaki Sb.( aDivision of Molecular Genetics, Clinical Research Center, Chiba-East National Hospital, bDepartment of Nephrology, Tokyo Medical and Dental University) Renal Week 2009, American Society of Nephrology, 2009/11, San Diego, USA
4. A NPC Motif of AQP11, Instead of the NPA Motif of Known AQPs, Has an
Important Role in Its Water Permeability: Ikeda M a, Taki A a, Muta K a, Kawano S a, Takamatsu N a, Ito K a, Ishibashi K, (a Veterinary Pharmacology, University of Miyazaki) Renal Week 2009, American Society of Nephrology, 2009/11, San Diego, USA
3）国内学会
一般講演・ポスター発表
1. 細胞内オルガネラにおけるマウスアクアポリン11 によるイオン環境の制御：田中靖子、廣川岳士、近藤信太郎、原繁樹、石橋賢一、日本薬学会第129 年会、2009/3、京都
2. 哺乳類アクアポリン10 (AQP10) 遺伝子の偽遺伝子化：近藤信太郎、原繁樹、野崎憲真、田中靖子、石橋賢一、日本薬学会第129 年会、2009/3、京都
3. AQP11 ノックアウトマウスにおけるprimary cilia の解析：小林克樹a、石橋賢一、内田信一ｂ、佐々木成ｂ （a 千葉東病院・臨床研究センター、ｂ東京医科歯科大学・腎臓内科）、第52 回日本腎臓学会学術総会、2009/6、横浜
4. アクアポリン11 による細胞内オルガネラのイオン環境の制御：石橋賢一、田中靖子、廣川岳士、近藤信太郎、原繁樹、第52 回日本腎臓学会学術総会、2009/6、横浜

1. 特別講演：水チャネルの病態生理学的役割：石橋賢一、埼玉体液カンファランス、2009/7、大宮

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ORIGINAL ARTICLE
 -1. Calcitriol Controls the Epithelial Calcium Channel in Kidney
JOOST G. J. HOENDEROP*, DOMINIK MÜLLER*, ANNEMIETE W. C. M. VAN DER KEMP*, ANITA HARTOG*, MAKOTO SUZUKI§, KENICHI ISHIBASHI§, MASASHI IMAI§, FRED SWEEP‡, PETER H. G. M. WILLEMS†, CAREL H. VAN OS* and RENÉ J. M. BINDELS*J Am Soc Nephrol 12:1342-1349, 2001
-2. A molecular mechanism for aberrantCFTR-dependent HCO3- transport in cystic fibrosis
Shigeru B.H. Ko1,2,5, Nikolay Shcheynikov1,5, Joo Young Choi1,5, Xiang Luo1, Kenichi Ishibashi3, Philip J. Thomas1, Joo Young Kim4, Kyung Hwan Kim4, Min Goo Lee4, Satoru Naruse2 and Shmuel Muallem1. The EMBO Journal (2002) 21, 5662 - 5672
-3. Ishibashi, K*., Kuwahara, M., Kageyama, Y., Sasaki, S., Suzuki, M., Imai, M. Molecular       cloning of a new aquaporin superfamily in mammals. p123-126, In “Molecular Biology and        Physiology of Water and Solute Transport” edited by Hohmann, S., and Nielsen S. Kluwer    Academic/Plenum Publishers, 2000.
-4. Ishibashi K, Matsuzaki T, Takata K, Imai M. Identification of a new member of type I Na/phosphate co-transporter in the rat kidney. Nephron Physiol. 2003;94(1):p10-8. pdf

1. Takeda S, Takahashi M, Mizukami H, Kobayashi E, Takeuchi K, Hakamata Y, Kaneko T, Yamamoto H, Ito C, Ozawa K, Ishibashi K, Matsuzaki T, Takata K, Asano Y, and Kusano E Successful Gene Transfer Using Adeno-Associated Virus Vectors into the Kidney: Comparison among Adeno-Associated Virus Serotype 1 to 5 Vectors In Vitro and In Vivo. Nephron Exp Nephrol. 96(4):e119-26, 2004.

2. Saito K, Kageyama Y,Okada Y, Kawakami S, Kihara K, Ishibashi K, Sasaki S. Localization of aquaporin-7 in human testis and ejaculated sperm: possible involvement in maintenance of sperm quality. J. Urol. 172: 2073-2076, 2004.

3. Yasushi Okamura, Atsuo Nishino, Yoshimichi Murata, Koichi Nakajo, Hirohide Iwasaki, Yukio Ohtsuka, Motoko Tanaka-Kunishima, et al, Comprehensive analysis of the ascidian genome reveals novel insights into the molecular evolution of ion channel genes. Physiological Genomics, 22: 269-282, 2005.

4. Li H, Kamiie J, Morishita Y, Yoshida Y, Yaoita E, Ishibashi K, Yamamoto T. Expression and Localization of Two Isoforms of AQP10 in Human Small Intestine. Biology of the Cell. 97:823-829, 2005.

5. Wakaumi M, Ishibashi K, Ando A, Kasanuki H, Tsuruoka S. Acute digoxin loading reduces ABCA8a mRNA expression in the mouse liver. Clinical and Experimental Pharmacology and Physiology, 32: 1034-101, 2005.

6. Itoh T, Rai T, Kuwahara M, Ko SB, Uchida S, Sasaki S, Ishibashi K. Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells. Biochem Biophys Res Commun. 330:832-838, 2005.

7. Morishita Y, Matsuzaki T, Hara-chikuma M, Andoo A, Shimono M, Matsuki A, Kobayashi K, Ikeda M, Yamamoto T, Verkman AS, Kusano E, Ookawara S, Takata K, Sasaki S , Ishibashi K Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Mol. Cell. Biol. 25:7770-7779, 2005.

8. Nakakoshi M, Morishita Y, Usui K, Ohtsuki M, Ishibashi K. Identification of a keratinocarcinoma cell line expressing AQP3. Biology of the Cell. 98:95-100, 2006.

9. Yakata K, Hiroaki Y, Ishibashi K, Sohara E, Sasaki S, Mitsuoka K, Fujiyoshi Y. Aquaporin-11 containing a divergent NPA motif has normal water channel activity. Biochim Biophys Acta. 1768: 688-693, 2007.

10. Okada S, Misaka T, Tanaka Y, Matsumoto I, Ishibashi K, Sasaki S, Abe K. Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation. FASEB J Oct;22(10):3672-84, 2008

11.  Hayakawa S, Mori M, Okuta A, Kamegawa A, Fujiyoshi Y, Yoshiyama Y, Mitsuoka K, Ishibashi K, Sasaki S, Hattori T, Kuwabara S. Neuromyelitis optica and anti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay. J Neuroimmunol, 2008 May 30;196(1-2):181-7

12. Tchekneva EE, Khuchua Z, Davis LS, Kadkina V, Dunn SR, Bachman S, Ishibashi K, Rinchik EM, Harris RC, Dikov MM, Breyer MD.　Single amino acid substitution in aquaporin 11 causes renal failure. J Am Soc Nephrol. 2008 Oct;19(10):1955-64.pdf

13. Ohta E, Itoh T, Nemoto T, Kumagai J, Ko SB, Ishibashi K, Ohno M, Uchida K, Ohta A, Sohara E, Uchida S, Sasaki S, Rai T. Pancreas-specific aquaporin 12 null mice showed increased susceptibility to caerulein-induced acute pancreatitis.Am J Physiol Cell Physiol. 2009 Dec;297(6):C1368-78.pdf

14.Ikeda M, Andoo A, Shimono M, Takamatsu N, Taki A, Muta K, Matsushita W, Uechi T, Matsuzaki T, Kenmochi N, Takata K, Sasaki S, Ito K, Ishibashi K. The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function. J Biol Chem. 2011 Feb 4;286(5):3342-50.

15. Morishita Y, Hanawa S, Miki T, Sugase T, Sugaya Y, Chinda J, Iimura O, Tsunematsu S, Ishibashi K, Kusano E. The association of plasma prorenin level with an oxidative stress marker, 8-OHdG, in nondiabetic hemodialysis patients. Clin Exp Nephrol. 2011 Jan 15. 15(3):398-404

16. Morishita Y, Ohnishi A, Watanabe M, Ishibashi K, Kusano E.　Establishment of acute kidney injury mouse model by 0.75% adenine ingestion.　Ren Fail. 2011;33(10):1013-8.
17. Morishita Y, Watanabe M, Nakazawa E, Ishibashi K, Kusano E.　The interaction of LFA-1 on mononuclear cells and ICAM-1 on tubular epithelial cells accelerates TGF-β1-induced renal epithelial-mesenchymal transition. PLoS One. 2011;6(8):e23267.

18.

Aquaporin-11 Expression in the Brain: Choroid Plexus and Capillaries with Blood-Brain Barrier Function

    Author/Faculty: Shin Koike, Yasuko Tanaka, Yoshiyuki Morishita, MD, PhD, Kenichi Ishibashi,

Generation and Analyses of AQP11 BAC Transgenic Mice

    Author/Faculty: Yuichi Inoue, MD, Eisei Sohara, MD, PhD, Katsuki Kobayashi, MD, PhD, Tatemitsu Rai, MD, PhD, Kenichi Ishibashi, MD, Sei Sasaki, MD, Shinichi Uchida, MD, PhD


REVIEWS

-1. The Dichotomy of MIP Family Suggests Two Separate Origins of Water Channels
Kenichi Ishibashi and Sei Sasaki . News in Physiological Sciences, Vol. 13, No. 3, 137-142, June 1998

-2.  Ishibashi, K*., Kuwahara, M., Kageyama, Y., Sasaki, S., Suzuki, M., Imai, M. Molecular cloning of a new aquaporin superfamily in mammals. p123-126, In “Molecular Biology and Physiology of Water and Solute Transport” edited by Hohmann, S., and Nielsen S. Kluwer    Academic/Plenum Publishers, 2000. pdf

1. Morishita Y, Sakube Y, Sasaki S, Ishibashi K. Aquaporin superfamily (superaquaporins): Expansion of aquaporins restricted to multicellular organisms. J Pharmacol. Sci. 96: 276-279, 2004

2. Ishibashi K, Ishikawa Y. Molecular Mechanisms and Drug Development in Aquaporin Water Channel Diseases: Preface. J. Pharmacol. Sci 96: 247-248, 2004.

3. Ishibashi K. Aquaporin subfamily with unusual NPA boxes. Biochimica et Biophysica Acta. 1758: 989-993, 2006

4. Ishibashi K. Aquaporin superfamily with unusual NPA boxes: S-aquaporins (superfamily, SIP-like and subcellular aquaporins). Cellular Molecular Biology 52(9): 20-27, 2006

5. Nozaki K, Ishii D, Ishibashi K. Intracellular aquaporins: clues for intracellular water transport? Pflugers Arch.  456: 701-707, 2008 pdf

6. Ishibashi K. New members of mammalian aquaporins: AQP10-AQP12. Handbook of Experimental Pharmacology 190: 251-262, 2009

７，Ishibashi K, Hara S, Kondo S.　Aquaporin water channels in mammals.　Clin Exp Nephrol.13: 107-117, 2009 pdf

8. Ishibashi K, Koike S, Kondo S, Hara S, Tanaka Y. The role of a group III AQP, AQP11 in intracellular organelle homeostasis. J. Med. Invest. 56 suppl.: 312-317, 2009.pdf

9. Ishibashi K, Kondo S, Hara S, Morishita Y. The evolutionary aspects of aquaporin family.Am J Physiol Regul Integr Comp Physiol. 2011 Mar;300(3):R566-76. pdf

1. 石橋賢一：水チャネルの構造と機能。別冊・医学のあゆみ10/24「イオンチャネル最前線update」156-161 : 2005

2. 石橋賢一：水チャネルと病気：アクアポリン病の病態生理。体液・代謝管理21: 21-28, 2005.

3. 石橋賢一：アクアポリンノックアウトマウスの多嚢胞腎形成機構の解明。厚生労働科学研究補助金難治性疾患克服研究事業「進行性腎障害に関する調査研究」平成１６年度総括・分担研究報告書117-119, 2005.

4. 石橋賢一：アクアポリン水チャネルと疾患。医学のあゆみ216: 705-711, 2006.

5. 石橋賢一：水チャネルの比較生物学。生体の科学　57: 476-477, 2006.

6.連載：　石橋賢一：語源で覚える薬物名（１〜１２）。レジデントノート：２００５年３月号から２００６年２月号まで１２回連載。

7. 巻頭言：石橋賢一：腎臓研究のゆくえ。腎と透析60: 389-390, 2006

8. 近藤信太郎、石橋賢一：電解質は無水では存在し得ない―水和と自由水 腎と透析　7月号, 2008

9．石橋賢一：腎臓と薬と薬剤師。明薬会誌１８９：１９－２２、２００８

10．石橋賢一：水チャネルの多彩な機能。明治薬科大学研究紀要３７：１－１０、２００８

１1.石橋賢一：アクアポリン水チャネルの多彩な機能とその障害　バイオフィリア　vol.14(4): 45-48、２００８
１２、石橋賢一：水チャネルと体液調節の異常。Current Therapy 27: 52-55, 2009
13．石橋賢一：大学院特論講義：水電解質研究の進歩。明治薬科大学研究紀要３８：２１－２８、２００９

14. 石橋賢一：大学院臨床医学特論講義：腎不全の病態生理からみた薬物療法の進歩　明治薬科大学研究紀要３９：１４－１８、２０１０

15.

田中靖子助教

1. 分化特異的転写因子または幹細胞特異的転写因子の強制発現による線維芽細胞

株の多能性変化とその後成的修飾効果： 田中資子、田中靖子、宮山絵里、勝沼亜紀

、設楽紘史、 日本生理学会第84回年会、2007/3、大阪

2. 幹細胞発現因子Nanog導入による線維芽細胞株の脱分化： 田中靖子、設楽紘史

、田中資子 日本薬学会第127年会、2007/3、富山

学位論文
修士（薬学）（平成２０年３月）


･　野崎憲真　Nozaki Kenma


ウシのアクアポリン10 （AQP10）遺伝子は偽遺伝子であるBos Taurus Aquaporin 10 (AQP10) Gene is a Pseudogene


・　石井大士 Ishii Daishi


2連続型カチオンチャネルの組織分布Tissue Distribution of Two-Pore Channel Family


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