2017
原著論文
  1. Impact of the dissolution profile of the cilostazol cocrystal with supersaturation on the oral bioavailability: Yoshimura Ma,b,Miyake Ma, Kawato Ta, Bando Ma, Kato Ya, Fukami T, Ozeki Tb (aOtsuka Pharmaceutical Co.,Ltd.,b Graduate School of Pharmaceutical Sciences, Nagoya City University), Cryst. Growth Des. 17, 550-557 (2017)
  2. In situ monitoring of crystalline transformation of carbamazepine using probe type low frequency Raman spectroscopy: Inoue M, Hisada H, Koide Ta, Carriere Jb, Heyler Rb, Fukami T (aDivision of Drugs, National Institute of Health Sciences, bOndax Inc.), Org. Process Res. Dev. 21, 262-265 (2017)
  3. Stability of mixed preparation consisting of commercial moisturizing creams with an ointment base investigated by magnetic resonance imaging: Onuki Ya, Funatani Cb, Yamamoto Yc, Fukami T, Koide Td, Hayashi Ya, Takayama Kb (aFaculty of Pharmacy and Pharmaceutical Science, University of Toyama, bDepartment of Pharmaceutics, Hoshi University,cFaculty of Pharmaceutical Science, Teikyo Heisei University,d Division of Drugs, National Institute of Health Sciences), Chem. Pharm. Bull. 65, 487-491 (2017)
  4. Novel amino acid-based surfactant for silicone emulsification and its application in hair care products: a promising alternative to quaternary ammonium cationic surfactants: Fujii M, Inoue M, Fukami T, Int. J. Cosmet. Sci. 39, 556-563 (2017)
  5. Comparison of pharmaceutical properties among clobetasol propionate cream formulations: Considerations from near infrared spectra: Yamamoto Ya, Fukami T, Onuki Yb, Metori Kc, Suzuki Td,Koide Te (aFaculty of Pharmaceutical Science, Teikyo Heisei University,bFaculty of Pharmacy and Pharmaceutical Science, University of Toyama, cChemical Analysis Center, Research Institute of Pharmacy, Nihon University, d Laboratory of Pharmaceutics, School of Pharmacy, Nihon University, eDivision of Drugs, National Institute of Health Sciences),Vib. Spectrosc. 93, 17-22 (2017)
  6. 共結晶を含む医薬品のレギュレーションに関する考察と一提言−共結晶体は原薬か製剤中間体か: 深水啓朗, 谷田智嗣a, 小出達夫b, 我藤勝彦c, 小野誠d, 岩尾康範e, 東顕二郎f, 池田幸弘g, 米持悦生h (a中外製薬株式会社 研究本部, b国立医薬品食品衛生研究所 薬品部, cアステラス製薬株式会社 技術本部 物性研究所, d 第一三共株式会社 製薬技術本部 分析評価研究所, e静岡県立大学薬学部 創剤工学教室, f千葉大学大学院薬学研究院 製剤工学研究室, g武田薬品工業株式会社ファーマシューティカル・サイエンス アナリティカル・デベロップメント, h星薬科大学 薬品物理化学教室), 医薬品医療機器レギュラトリーサイエンス accepted (2017)
  7. Real-Time Formation Monitoring of Cocrystals with Different Stoichiometries Using Probe-Type Low-Frequency Raman Spectroscopy: Inoue M, Hisada H, Koide Ta, Carriere Jb, Heyler Rb, Fukami T (aDivision of Drugs, National Institute of Health Sciences, bOndax Inc.), Ind. Eng. Chem. Res. in press (2017)
  8. Comparison of the Relative Stability of Pharmaceutical Cocrystals Consisting of Paracetamol and Dicarboxylic Acids: Suzuki Na, Kawahata Mb, Yamaguchi Kb, Suzuki Ta, Tomono Ka, Fukami T (aLaboratory of Pharmaceutics, School of Pharmacy, Nihon University, bFaculty of Pharmaceutical Sciences, Tokushima Bunri University Kagawa Campus), Drug Devel. Ind. Pharm. accepted (2017)

2016
原著論文
  1. Pharmaceutical evaluation of atorvastatin calcium tablets available on the Internet: a preliminary investigation of substandard medicines in Japan: Fukami T, Koide Ta, Hisada H, Inoue M, Yamamoto Yb, Suzuki Tc, and Tomono Kc, (aDivision of Drugs, National Institute of Health Sciences, bFaculty of Pharmaceutical Science, Teikyo Heisei University, cSchool of Pharmacy, Nihon University), J. Drug. Deliv. Sci. Tech. 31, 35-40 (2016)
  2. Analysis of the stability of external-application dermatologic preparations: consideration from rheological measurement: Yamamoto Ya, Kumetani Ma, Onuki Yb, Koide Tc, Suzuki Td, Fukami T, (aFaculty of Pharmaceutical Science, Teikyo Heisei University, b Faculty of Pharmacy and Pharmaceutical Science, University of Toyama, c Division of Drugs, National Institute of Health Sciences,d School of Pharmacy, Nihon University),Chem. Pharm. Bull. 64, 1047-1055 (2016)
  3. Involvement of a proton-coupled organic cation antiporter in the blood-brain barrier transport of amantadine: Suzuki Ta, Aoyama Ta, Suzuki Na, Fukami T, Matsumoto Ya, Tomono Ka (aSchool of Pharmacy, Nihon University), Biopharm. Drug Dispos. 37, 323-335 (2016)
  4. Characterization and quality control of pharmaceutical cocrystals (Review article): Izutsu Ka, Koide Ta, Takata Nb, Ikeda Yc, Ono Md, Inoue M, Fukami T, Yonemochi Ee, (a National Institute of Health Sciences, b Research Division, Chugai Pharmaceutical Co., Ltd., c Analytical Development Laboratories, CMC Center, Takeda Pharmaceutical Co., Ltd., d Analytical & Quality Evaluation Research Laboratories, Daiichi-Sankyo Co., Ltd., e School of pharmacy and Pharmaceutical Sciences, Hoshi University), Chem. Pharm. Bull. 64, 1421-1430 (2016)
  5. Solid dispersions of efonidipine hydrochloride ethanolate with improved physicochemical and pharmacokinetic properties prepared with microwave treatment: Otsuka Ma,Maeno Ya, Fukami T, Inoue M, Tagami Tb and Ozeki Tb (aAnalysis Research Department, Chemical Research Laboratories, Nissan Chemical Industries, Ltd., b Graduate School of Pharmaceutical Sciences, Nagoya City University), Eur. J. Pharm. Biopharm. 108, 25-31 (2016)
  6. Microanalysis of pharmaceutical cocrystals using a nano-spot method coupled with Raman spectroscopy: Maeno Ya, Inoue M, Suzuki Tb, Tomono Kb, Fukami T, (aAnalysis Research Department, Nissan Chemical Industries, Ltd.,b Laboratory of Pharmaceutics, School of Pharmacy, Nihon University),CrystEngComm 18, 8004-8009 (2016)
  7. Identification of pseudopolymorphism of magnesium stearate by using low frequency Raman spectroscopy: Koide Ta, Fukami T, Hisada H, Inoue M, Carriere Jb, Heyler Rb, Katori Na, Okuda Ha, Goda Ya(aDivision of Drugs, National Institute of Health Sciences, bOndax Inc.), Org. Process Res. Dev. 20, 1906-1910 (2016)
招待講演
  1. Symposia: Pharmaceutical evaluation of atorvastatin calcium tablets available on the Internet: Fukami T, Hisada H, Inoue M, Koide Ta (aDivision of Drugs, National Institute of Health Sciences), The Great Scientific Exchange SCIX2016, 2016/9, Minneapolis, Minnesota, USA
  2. Symposia: Real-time monitoring of crystalline compounds using in situ low frequency Raman probe: Inoue M, Hisada H, Koide Ta, Fukami T(aDivision of Drugs, National Institute of Health Sciences), The Great Scientific Exchange SCIX2016, 2016/9, Minneapolis, Minnesota, USA

2015
原著論文
  1. Possible involvement of cationic-drug sensitive transport systems in the blood-to-brain influx and brain-to-blood efflux of amantadine across the blood-brain barrier: Suzuki Ta, Fukami T and Tomono Ka (aSchool of Pharmacy, Nihon University), Biopharm. Drug Dispos. 36, 126-137 (2015)
  2. ヘパリン類似物質含有軟膏の塗布におけるエルロチニブ誘発皮膚障害の発現時期に及ぼす性別の影響: 宗 村盛a, 鈴木豊史b, 藤井瑞恵a, 井上真由美a, 長島修c, 深水啓朗, 伴野和夫b,(a順天堂大学医学部附属順天堂東京江東高齢者医療センター薬剤科, b日本大学薬学部薬剤学研究室c順天堂大学医学部附属順天堂東京江東高齢者医療センター呼吸器内科), 日病薬師会誌 51, 216-219 (2015)
  3. Studies on Uniformity of the Active Ingredients in Acetaminophen Suppositories Re-solidified after Melting under High Temperature Conditions: Yamamoto Ya, Fukami T, Koide Tb, Onuki Yc, Suzuki Td, Katori Nb and Tomono Kd (aFaculty of Pharmaceutical Sciences, Teikyo Heisei University, bDivision of Drugs, National Institute of Health Sciences, cDepartment of Pharmaceutics, Hoshi University, dSchool of Pharmacy, Nihon University), Chem. Pharm. Bull. 63, 263-272 (2015)
  4. Magnetic Resonance Imaging of the Phase Separation in Mixed Preparations of Moisturizing Cream and Steroid Ointment after Centrifugation: Onuki Ya, Funatani Ca, Yokowa Tb, Yamamoto Yc, Fukami T, Koide Td, Obata Ya and Takayama Ka (aDepartment of Pharmaceutics, Hoshi University, bBio View Corporation, cFaculty of Pharmaceutical Sciences, Teikyo Heisei University, dDivision of Drugs, National Institute of Health Sciences), Chem. Pharm. Bull. 63, 326-329 (2015)
  5. 医薬品の原薬形態である塩と共結晶のレギュレーションに関する現状と提言:深水啓朗, 山下博之a, 小野誠b, 池田幸弘c (aアステラス製薬株式会社 研究本部 薬物動態研究所, b第一三共株式会社 製薬技術本部 分析評価研究所, c武田薬品工業株式会社 CMC研究センター 開発分析研究所), 医薬品医療機器レギュラトリーサイエンス 46, 326-329 (2015)
  6. Analysis of Distribution of Ingredients in the Clarithromycin Tablet in the Market by Using Near-Infrared Chemical Imaging with Principal Component Analysis and Partial Least Squares: Koide Ta, Yamamoto Yb, Fukami T, Katori Na, Okuda Ha and Hiyama Ya (aDivision of Drugs, National Institute of Health Sciences, bFaculty of Pharmaceutical Sciences, Teikyo Heisei University), Chem. Pharm. Bull. 63, 663-668 (2015)
  7. Determination and prediction of solubilities of active pharmaceutical ingredients in selected organic solvents: Matsuda Ha, Mori Ka, Tomioka Ma, Kariyasu Na, Fukami T, Kurihara Ka, Tochigi Ka and Tomono K b, (aDepartment of Materials and Applied Chemistry, Nihon University, bSchool of Pharmacy, Nihon University), Fluid Phase Equilibria 406, 116-123 (2015)
  8. Developmental considerations for ethanolates with regard to stability and physicochemical characterization of efonidipine hydrochloride ethanolate: Otsuka Ma,Maeno Ya, Fukami T, Inoue M, Tagami Tb and Ozeki Tb (aAnalysis Research Department, Chemical Research Laboratories, Nissan Chemical Industries, Ltd., b Graduate School of Pharmaceutical Sciences, Nagoya City University), CrystEngComm. 17, 7430-7436 (2015)
  9. Direct High-Resolution Imaging of Crystalline Components in Pharmaceutical Dosage Forms Using Low-Frequency Raman Spectroscopy: Hisada H, Inoue M, Koide Ta, Carriere Jb, Heyler Rb, and Fukami T (aDivision of Drugs, National Institute of Health Sciences, bOndax Inc.), Org. Process Res. Dev. 19, 1796-1798 (2015)
招待講演
  1. シンポジウム実用段階に到達した医薬品共結晶の基礎と最新動向:深水啓朗, 第33回物性物理化学研究会, 2015/6, 京都
  2. Symposia: Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former :Fukami T, ACHEMA2015, IPNF2015, 2015/6, Frankfurt, Germany
  3. Symposia: Chemical Imaging of Crystalline Components in Pharmaceutical Dosage Forms by Using Low Frequency Raman Spectroscopy: Fukami T, Hisada H, Inoue M, Koide Ta (aDivision of Drugs, National Institute of Health Sciences), The Great Scientific Exchange SCIX2015, 2015/9, Providence, Rhode Island, USA
  4. Symposia: Development of Useful Tools for Advancing Pharmaceutical Cocrystals: Fukami T, INCHEM TOKYO 2015 Germany-Japan Forum for Innovative Products and Technology, 2015/11, Tokyo, Japan

2014
原著論文
  1. Comparative pharmaceutical evaluation of brand and genericclobetasone butyrate ointments: Yamamoto Ya, Fukami T, Koide Tb, Onuki Yc, Suzuki Td, Metori Kd, Katori Nb, Hiyama Yb and Tomono Kd (aFaculty of Pharmaceutical Sciences, Teikyo Heisei University, bDivision of Drugs, National Institute of Health Sciences, cDepartment of Pharmaceutics, Hoshi University, dSchool of Pharmacy, Nihon University), Int. J. Pharm. 463, 62-67 (2014)
  2. Novel pharmaceutical cocrystal consisting of paracetamol and trimethylglycine, a new promising cocrystal former: Maeno Ya, Fukami T, Kawahata Mb, Yamaguchi Kb, Tagami Tc, Ozeki Tc, Suzuki Td and Tomono Kd (aAnalysis Research Department, Chemical Research Laboratories, Nissan Chemical Industries, Ltd., bFaculty of Pharmaceutical Sciences at Kagawa Campus, Tokushima Bunri University, cGraduate School of Pharmaceutical Sciences, Nagoya City University, dSchool of Pharmacy, Nihon University), Int. J. Pharm. 473, 179-186 (2014)
招待講演
  1. Symposia: Suitability of Ultralow Frequency Raman Spectroscopy for pharmaceutical evaluation: Koide Ta and Fukami T (aDivision of Drugs, National Institute of Health Sciences), The Great Scientific Exchange SCIX2014, 2014/10, Reno-Tahoe, Nevada, USA
  2. シンポジウム医薬品Cocrystalの微量探索スクリーニグ:深水 啓朗、愛知学院大学薬学部医療生命薬学研究所 第2回サイエンス・フォーラム、2014/3、名古屋