Pharmacodynamics
Masaru SHOJI, M.D., Ph.D., Professor
Mitsuo MITA, Ph.D., Associate Professor
Shigeru HISHINUMA, Ph.D., Associate Professor
The Department of Pharmacodynamics participates in several graduate and undergraduate educational programs for health professionals in community, hospital, industrial, and academic pharmacy. Our teaching staffs are also active researchers. In association with established pharmacological, biochemical and physiological methods, the application of updated molecular technologies makes it possible to characterize older drugs further and to discover new mechanisms and key molecules faster than ever. In the search for new potential therapeutic agents and biomarkers, we are involved in the following research projects:
1. Elucidating the specific cellular signaling and molecular mechanisms underlying vascular endothelial dysfunction in cultured vascular endothelial cells and in lifestyle-related diseases
2. Investigating the intracellular signal transduction and key molecules in contractile properties of arterial smooth muscle under physiological and pathophysiological conditions
3. Molecular determination of membrane receptor signaling plasticity and its mechanisms in genetically modified culture cell lines
