Hirotoshi ECHIZEN, M.D., Ph.D., Professor
Ryuichi OGAWA, Ph.D, Assistant Professor
Masahiro TAKAHASHI,M.Pharm., Research Associate
Pharmacotherapy is a hybrid clinical discipline consisting of pharmaceutical sciences, medicine and clinical pharmacology. Our research scope encompasses from pharmacogenomic studies of population differences in pharmacokinetic and dynamics of an anticoagulant, warfarin and of interindividual variability in the sodium channel blocking effects of a Class IC antiarrhythmic agent, pilsicainide, to studies aimed at the quantitative prediction of drug interactions via various mechanisms of metabolic inhibition. Our recent research interests cover studies with the use of meta-analysis of various clinical topics for establishing an evidence-based approach in pharmacotherapy. Our ultimate goal is to establish a robust scientific basis for personalized medicine for every patient via research in pharmacotherapy. We have also been deeply involved in the education of clinical pharmacists for graduate students coming throughout Japan since 1995 in collaboration with the School of Pharmacy, University of Illinois at Chicago, USA.